Professor Dean’s research involves in vitro and bioinformatic approaches along with studies of human populations to address host-pathogen interactions, including bacterial genomics, host immune responses and microbiota/microbiome/metabolome associations with disease protection and pathogenesis related to the obligate intracellular bacterium Chlamydia trachomatis. Her group was the first to identify genomic recombination in this human pathogen. The Dean lab also studies the evolution of zoonotic chlamydial species.